Endocrine disrupting mechanisms and effects of pesticides

Endocrine Disrupting Pesticides

Effects of Endocrine Disrupting Chemicals on Seals

At the same time harbour porpoises, that had died of a similar virus, appeared stranded on the beaches. Two years later another mass die-off occurred in the Mediterranean striped dolphin populations. The severe and lethal outcomes of the epidemics led many in the scientific community to believe that a contaminantinduced immune deficiency was responsible for the high mortality during the epidemi...

Endocrine-Disrupting Chemicals: Associated Disorders and Mechanisms of Action

The incidence and/or prevalence of health problems associated with endocrine-disruption have increased. Many chemicals have endocrine-disrupting properties, including bisphenol A, some organochlorines, polybrominated flame retardants, perfluorinated substances, alkylphenols, phthalates, pesticides, polycyclic aromatic hydrocarbons, alkylphenols, solvents, and some household products including s...

Physiological effects and mechanisms of action of endocrine disrupting chemicals that alter estrogen signaling.

Address for correspondence: Kenneth S. Korach, Ph.D., Receptor Biology Section, Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental Health Sciences, National Institutes of Health, MD B3-02, P.O. Box 12233, Research Triangle Park, NC 27709 USA, Tel.: (919) 541-3512, Fax: (919) 541-0696, e-mail: [email protected] Received 10-02-10, Revised 20-05-10, Acc...

Organizational and activational effects of estrogenic endocrine disrupting chemicals.

Endocrine disruption is a hypothesis of common mode of action that may define a set of structurally varied chemicals, both natural and synthetic. Their common mode of action may suggest that they produce or contribute to similar toxic effects, although this has been difficult to demonstrate. Insights from developmental biology suggest that development of hormone sensitive systems, such as the b...